Histone Proteases: the Tale of Tail Clippers
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چکیده
In the histone code hypothesis histone proteolysis is depicted as a novel kind of irreversible post-translational modifications of histones. Site specific proteolysis of histone is hypothesized as a process for removal of epigenetic signature of histones. However, though there are many reports depicting histone proteolysis, there are very few reports on characterization of a histone protease. In the present review we tend to summarize classify the existing histone proteases and we also discuss the role of these proteases in modulation of chromatin structure and function.
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تاریخ انتشار 2012